Cover of: Molecular mechanisms in gastrointestinal cancer | B. Mark Evers

Molecular mechanisms in gastrointestinal cancer

  • 112 Pages
  • 3.64 MB
  • 8136 Downloads
  • English
by
R.G. Landes , Austin, Tex
Oncology, HEALTH & FITNESS, Diseases, Cancer, Molecular aspects, Gastrointestinal system, ME
Statement[edited by] B. Mark Evers
SeriesMedical intelligence unit -- 12, Medical intelligence unit -- 12.
Classifications
LC ClassificationsRC280.D5 M635 1999eb
The Physical Object
Format[electronic resource] /
Pagination1 online resource (112 p.)
ID Numbers
Open LibraryOL27075784M
ISBN 100585408777
ISBN 139780585408774
OCLC/WorldCa50322001

Molecular Mechanisms In Gastrointestinal Cancer: Medicine & Health Science Books @ COVID Resources. Reliable information about the coronavirus (COVID) is available from the World Health Organization (current situation, international travel).Numerous and frequently-updated resource results are available from this ’s WebJunction has pulled together information and resources to assist library staff as they consider how to handle coronavirus.

Molecular understanding of gastrointestinal cancer has come a long way since the first ‘Vogelgrams.’ In part, this reflects the success of the human genome project and the development of high throughput molecular assays.

This book, which is part of the Molecular Pathology Library series, aims to update readers on the current state of our understanding of molecular pathology in Author: Mojgan Hosseini–Varnamkhasti, Jerrold R.

Turner. Genre/Form: Electronic books: Additional Physical Format: Print version: Molecular mechanisms in gastrointestinal cancer. Austin, Tex.: R.G. Landes, © The molecular characterization of the steps of gastrointestinal neoplastic development and progression has led to advances in disease diagnosis and treatment and has opened the opportunity for development of more targeted approaches to cancer prevention, surveillance, and novel therapeutics.

This Special Issue aims to address the role of etiological factors, such as Helicobacter pylori infection, the microbiome, and other environmental factors in gastric cancer, emphasizing their molecular mechanisms of action.

It also aims to explore the distinct molecular profiles associated with gastric carcinogenesis, including that associated. This book is about the manipulation of the immune system as a therapeutic approach to gastrointestinal cancer and its clinical applications, the genetic and molecular mechanisms which the tumour can use to escape immune control and regulation, is also discussed.

Gastrointestinal (GI) cancer is a prevailing global health disease with a high incidence rate which varies by region. It is a huge economic burden on health care providers. GI cancer affects different organs in the body such as the gastric organs, colon, esophagus, intestine, and pancreas.

Internal and external factors like smoking, obesity, urbanization, genetic mutations, and prevalence of. Molecular Mechanism and Morphology in Cancer eBook: US $59 Special Offer (PDF + Printed Copy): US $ Printed Copy: US $ Library License: US $ ISBN: (Print) ISBN: (Online) Year of Publication: DOI: / The only book that discusses cancer diagnosis, therapy, and prognosis together in one volume * Explains the molecular mechanisms underlying these cancers Metastatic Molecular mechanisms in gastrointestinal cancer book Cancer: Safety of Cisplatin Combined with Continuous 5-FU Versus Bolus 5.

This book is dedicated to my mentors: Raffaela and Joseph Pecorino Professor Frank Erk Professor Sidney Strickland Professor Jeremy Brockes In memory of: Marie Favia Mildred Maiello Kerry O’Neill.

This page intentionally left blank PREFACE Molecular Biology of Cancer: Mechanisms, Targets, and Therapeutics is intended for both undergraduate. This book provides the most comprehensive and up-to-date knowledge of lymph node micrometastasis (LMM) and sentinel node navigation surgery (SNNS) in gastrointestinal cancers.

Lymph node metastasis is a critically important prognostic factor in gastrointestinal tract cancers such as tumors of the esophagus, stomach, and colorectum. Physiology of the Gastrointestinal Tract, Fifth Edition — winner of a Highly Commended BMA Medical Book Award for Internal Medicine — covers the study of the mechanical, physical, and biochemical functions of the GI Tract while linking the clinical disease or disorder, bridging the gap between clinical and laboratory medicine.

The gastrointestinal system is responsible for the. Over the last three decades, knowledge on the molecular biology of human cancers has vastly expanded. A host of genes and proteins involved in cancer development and progression have been defined and many mechanisms at the molecular, cellular and even tissue level have been, at least partly, elucidated.

Description Molecular mechanisms in gastrointestinal cancer EPUB

Insights have also been gained into the molecular mechanisms underlying. Immunotherapy for Gastrointestinal Cancer [Kerr, David, Johnson, Rebecca] on *FREE* shipping on qualifying offers.

Immunotherapy for Gastrointestinal Cancer The reverse side of this equation, the genetic and molecular mechanisms which the tumour can use to escape immune control and regulation, is also discussed.

This book systematically reviews the most important findings on cancer immune checkpoints, sharing essential insights into this rapidly evolving yet largely unexplored research book offers a valuable resource for researchers in the cancer immunotherapy field.

Barber M, Murrell A, Ito Y, et al. Mechanisms and sequelae of E-cadherin silencing in hereditary diffuse gastric cancer. J Pathol ; Oliveira C, Sousa S, Pinheiro H, et al. Quantification of epigenetic and genetic 2nd hits in CDH1 during hereditary diffuse gastric cancer syndrome progression.

Concurrently, the development of targeted therapies and the optimization of already available chemotherapeutic drugs has expanded the available treatment options for advanced tumors.

This Special Issue will focus on both the molecular characterization and innovative molecularly-based targeted therapies in metastatic gastrointestinal tumors.

Liu et al. analyze gastrointestinal (GI) tract adenocarcinomas and find that hypermutated tumors are enriched for insertions/deletions, upper GI tumors with chromosomal instability harbor fragmented genomes, and a group of genome-stable colorectal tumors.

Molecular Basis of Diseases of the Gastrointestinal Tract Molecular basis of Liver Disease Molecular basis of diseases of the exocrine pancreas Molecular Basis of Diseases of the Endocrine System Molecular Basis of Gynecologic Diseases Molecular Basis of Kidney Disease Molecular Pathogenesis of Prostate Cancer Purchase Drug Resistance in Colorectal Cancer: Molecular Mechanisms and Therapeutic Strategies, Volume 8 - 1st Edition.

Print Book & E-Book. ISBNThe mechanisms responsible for drug refractoriness in gastrointestinal tumours include a reduction in drug uptake; enhanced drug export; intracellular inactivation of the effective agent; alteration of the molecular target; an increase in the activity of the target route to be inhibited or the appearance or stimulation of alternative routes.

The pathogenesis of gastric cancer remains poorly understood although it is evident that several environmental factors, such as H. pylori infection can be the cause leading to this disease. pylori infection is associated with risk for both the intestinal and diffuse varieties of gastric cancer.

In fact, the risk to develop gastric cancer is increased in patients with H. pylori infections. Handbook of Gastrointestinal Cancers is a practical guide to the management of colorectal, pancreatic, hepatocellular, gastric, and esophageal cancers as well as other cancers of the upper and lower gastrointestinal tract.

Edited by a multidisciplinary group of oncologists from leading institutions, this book is an essential day-to-day reference for evidence-based treatment and patient care. with a focus on mechanisms and biomarkers of pre-cancer and cancer lesions in the gastrointestinal tract and in the pancreas.

Thermo Fisher: Tell us about your research. Antonia Sepulveda: My research focus is on the molecular mechanisms that drive pre-cancer tissues to dysplasia and cancer, particularly in the gastrointestinal tract and pancreas.

Gastrointestinal cancers other than CRC and esophageal cancer rarely metastasize to the brain.

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Gastric cancer has been estimated to result in BM in % of cases (Table ), with median time to diagnosis of BM estimated to be 12 months (Table ). Over the last three decades, knowledge on the molecular biology of human cancers has vastly expanded.

A host of genes and proteins involved in cancer development and progression have been defined and many mechanisms at the molecular, cellular and even tissue level have been, at least partly, elucidated. New Aspects in Molecular and Cellular Mechanisms of Human Carcinogenesis. Edited by Written by an international team of experts in the field of human carcinogenesis, this book discusses recent advances in cancer research, which include the following topics: basic molecular and cellular mechanisms behind cancer growth, new approaches in cancer therapy, and cancer diagnostic.

Title:Understanding the Molecular Mechanisms of Rifaximin in the Treatment of Gastrointestinal Disorders – A Focus on the Modulation of Host Tissue Function VOLUME: 16 ISSUE: 3 Author(s):Simon A.

Hirota Affiliation Hospital Dr. NW – Health Sciences Room ; T2N 4N1, Canada. Keywords:Crohn’s disease, hepatic encephalopathy, infectious colitis, inflammatory bowel diseases.

‎This book is about the manipulation of the immune system as a therapeutic approach to gastrointestinal cancer and its clinical applications, exploring therapeutic approaches which might be taken under the broad banner of immunotherapy.

Starting by introducing concepts of modern immunology, the. This subject is addressed in five sections. The first section of the book presents the overview, the management of rectal and esophageal GIST, and Asian consensus guidelines.

The overview covers its unique biologic behavior, clinicopathological features, molecular mechanisms, and.

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This book provides the reader with an overall understanding of the biology of pancreatic cancer, hereditary, complex signaling pathways and alternative therapies. The book explains nutrigenomics and epigenetics mechanisms such as DNA methylation, which may explain the etiology or progression of pancreatic cancer.

Book also summarizes the molecular control of oncogenic .Immunotherapy for Gastrointestinal Cancer - Ebook written by David Kerr, Rebecca Johnson.

Read this book using Google Play Books app on your PC, android, iOS devices. Download for offline reading, highlight, bookmark or take notes while you read Immunotherapy for Gastrointestinal Cancer.